en Environmental Health, Sciences, and Engineering Original articles <div style="text-align: justify;"><span style="font-size:12pt"><span style="line-height:115%"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><b><i><span style="font-size:10.0pt"><span style="line-height:115%">Introduction:</span></span></i></b><span style="font-size:10.0pt"><span style="line-height:115%"> High concentrations of nitrate, nitrite, and fluoride in drinking water can cause adverse health effects. This study aims to investigate concentration and health risks assessment of nitrate, nitrite, and fluoride ions in water reservoirs of Mehriz city and Bahadoran district.</span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:115%"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><b><i><span style="font-size:10.0pt"><span style="line-height:115%">Materials and Methods:</span></span></i></b><span style="font-size:10.0pt"><span style="line-height:115%"> Monthly sampling was done from water reservoirs of Mehriz city and Bahadoran district for 6 months. Nitrate, nitrite, and fluoride concentrations were measured in the samples using a spectrophotometer. Then, health risk assessment and sensitivity analysis were performed on the obtained data using Crystal Ball software and Monte Carlo simulation method.</span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:115%"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><b><i><span style="font-size:10.0pt"><span style="line-height:115%">Results:</span></span></i></b><span style="font-size:10.0pt"><span style="line-height:115%"> Nitrate, nitrite, and fluoride concentrations were lower than the standard limitation in all of the studied areas. Risk assessment findings indicated that hazard quotient (HQ) values of nitrite in Miankoh-Movahedin, Bidok and Bahadoran water reservoirs were less than 1 for all age groups. HQ values of nitrate were also below 1 for all age groups except children. HQ values of fluoride in Bahadoran water reservoir were below 1 for all age groups except children.</span></span></span></span></span><br> <b><i><span style="font-size:10.0pt"><span style="line-height:107%"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Conclusion:</span></span></span></i></b><span style="font-size:10.0pt"><span style="line-height:107%"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"> Health risk of consuming water containing nitrates and fluorides is high for children. Based on sensitivity analysis, the concentration of nitrate and fluoride in drinking water is the key factor in raising health risks. Reducing nitrate and fluoride concentrations in drinking water can reduce health risks in the population.</span></span></span></div> Drinking Water, Health Risk Assessment, Nitrates, Fluorides,Mehriz City 2329 2340 http://jehsd.ssu.ac.ir/browse.php?a_code=A-10-171-8&slc_lang=en&sid=1 Ali Ghasemzadeh alighasemzade967@gmail.com 0000-0002-1522-7190 No Environmental Science and Technology Research Center, Department of Environmental Health Engineering, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Mohammad Taghi Ghaneian mtghaneian@gmail.com 0000-0002-6665-2226 No Environmental Science and Technology Research Center, Department of Environmental Health Engineering, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Reza Ali Fallahzadeh fallahzadeh4@yahoo.com 0000-0003-1107-4366 No Environmental Science and Technology Research Center, Department of Environmental Health Engineering, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Vahid Jafari Nodoshan jafarivahid94@gmail.com 0000-0003-0810-048X No Environmental Science and Technology Research Center, Department of Environmental Health Engineering, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Hossein Fallahzadeh fallahzadeh.ho@gmail.com 0000-0001-6518-366x No Center for Healthcare Data Modeling, Departments of Biostatistics and Epidemiology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Arash Dalvand arash.dalvand@gmail.com 0000-0002-6131-2169 Yes Environmental Science and Technology Research Center, Department of Environmental Health Engineering, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran