Journal of Environmental Health and Sustainable Development

en Effect of Dietary Clove (Syzygium Aromaticum) Essential Oil on Growth Performance, Oxidative Indices, Lipid Profile, and Cadmium Accumulation in Cd-exposed Quails Environmental toxicology Original articles <div style="text-align: justify;"><a name="_Hlk88088824"></a><a name="_Hlk88090153">Introduction</a>: Natural products can alleviate oxidative stress induced by toxic metals. This study evaluated antioxidant properties of clove essential oil (CEO), compared to oxidative deterioration of Cd. It was carried out by measuring growth performance parameters (BW, FI, and FCR), oxidative indices (TBARS, CP, CAT, SOD, and GPx), lipid profile (TG, TC, LDL-C, and HDL-C), and Cd bioaccumulation in quails.<a name="_Hlk88088692"></a> Materials and Methods: In this study, 480 Japanese quails were fed with diets for 35 days. The diets included basal diet, basal diet + VC (500 mg/kg), basal diet + CEO (450 mg/kg), basal diet + CEO (100 mg/kg), basal diet + VC (500 mg/kg) + Cd (40 mg/l), basal diet + CEO (450 mg/kg) + Cd (40 mg/l), basal diet + CEO (100 mg/kg) + Cd (40 mg/l), and basal diet + Cd (40 mg/l). Oxidative indices and Cd bioaccumulation (ICP-OES) were measured. Results: The major ingredients of CEO included Eugenol (77.63%) and β-Caryophyllene (9.55%).  Quails exposed to Cd and treated with CEO had a reduced amount of oxidative stress as evidenced by lower concentrations of TBARS and CP, higher activities of SOD, GPx, and CAT, an improved lipid profile, and lower accumulation of Cd compared to the positive control. However, FI and FCR did not change. Conclusion: Antioxidant properties of CEO were dose-dependent. CEO (450 mg/kg) was potentially as effective as, or even more potent than VC (500 mg/kg) in reducing the adverse effects of Cd. However, further studies are required to determine the minimum concentration of COE.</div> Cadmium Chloride, Oxidative Damage, Oxidative Stress, Quail. 1755 1766 http://jehsd.ssu.ac.ir/browse.php?a_code=A-10-470-1&slc_lang=en&sid=1 Elahe Askari dr.Askari2011@gmail 0000-0003-4735-4095 No Nutritional Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran. Aziz A. Fallah Fallah.aziz55@yahoo.com 0000-0003-3292-7647 No Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, Shahre-kord University, Shahre-kord, Iran. Saeid Habibian Dehkordi Habibian@vet.sku.ac.ir 0000-0003-3545-4566 No Department of Basic Sciences, Faculty of Veterinary Medicine, Shahre-kord University, Shahre-kord, Iran. Shahab Bahadoran bahadoran-s@sku.ac.ir 0000-0002-5897-8509 No Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahre-kord University, Shahre-kord, Iran. Abdonnaser Mohebbi mohebi-ab@sku.ac.ir 0000-0002-2645-4233 No Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahre-kord University, Shahre-kord, Iran. sara mohamadi saramohamadi12@yahoo.com 0000-0002-7703-9195 Yes Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, Shahre-kord University, Shahre-kord, Iran.