en تخصصي Special Systematic Review <p dir="ltr" style="text-align: justify; "><strong><em><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">Introduction:</span></span></em></strong><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;"> Antibiotics as a type of pharmaceutical compounds are widely used in modern medicine and veterinary industries. <a name="OLE_LINK2"></a><a name="OLE_LINK1">They enter the environment in different ways,</a> including agricultural runoff, direct discharge of urban wastewater treatment or human waste, direct disposal of medical, veterinary industrial waste and to name but a few. Antibiotics have been able to influence the microbial population. Their continuous presence in the environment can lead to bacterial resistance and in recent years, the issue has caused serious concerns in the scientific community.</span></span><br> <strong><em><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">Materials and Methods:</span></span></em></strong><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;"> Unfortunately, </span></span><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">in spite of the extensive investigations, there is still a considerable lack of integrated and classified information to assess the environmental risks of antibiotics. Therefore, in the current study, the removal of these compounds from aqueous solutions was studied. This study was carried out on the basis of surveys accomplished in recent decades and also the ones published in databases such as Google Scholar, PubMed, Elsevier, Scopus, Springer, Magiran and SID using anti-bacterial agents, antibiotic, wastewater and removal methods as the keywords.</span></span><br> <strong><em><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">Results:</span></span></em></strong><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;"> Advanced treatment processes such as ozonation, advanced oxidation, activated carbon, Nano filtration and reverse osmosis can remove higher levels of antibiotics.</span></span><br> <strong><em><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">Conclusion:</span></span></em></strong><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;"> Generally, the biological and chemical processes alone are not effective for antibiotics&#39; removal from aquatic environments while combination of advanced oxidation and biological treatment processes can effectively reduce the amount of antibiotic.</span></span><br> &nbsp;</p> Antibiotic Removal,Aqueous Solution,Environment. 43 62 http://jehsd.ssu.ac.ir/browse.php?a_code=A-10-1-6&slc_lang=en&sid=1 Zahra Derakhshan No Environmental Science and Technology Research Center, Department of Environmental Health Engineering, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Mehdi Mokhtari No Environmental Science and Technology Research Center, Department of Environmental Health Engineering, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Fatemeh Babaei No Environmental Science and Technology Research Center, Department of Environmental Health Engineering, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Roya Malek Ahmadi No Environmental Science and Technology Research Center, Department of Environmental Health Engineering, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Mohammad Hassan Ehrampoush No Environmental Science and Technology Research Center, Department of Environmental Health Engineering, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Mohammad Faramarzian mfaramarzi1985@gmail.com Yes Department of Environmental Health Engineering, Shiraz University of Medical Sciences, Shiraz, Iran.